【摘要】 目的探讨成人阻塞性睡眠呼暂停低通气综合征(obstructive sleep apnea hypopneasyndrome,OSAHS)对患者生活质量的影响因素。方法对9 3例OSAHS患者用中文版健康调查量表(SF-3 6)评估生活质量,白天嗜睡(excessive Daytime sleepiness,EDS)用Epworth睡眠评分法(epworth sleepiness scale,ESS)评分。对比研究SF-36量表中各维度得分和患者基本信息、多导睡眠监测(polysommography,PSG)各参数、EDS分值的关系,利用Pearson相关分析及多元回归分析法进行分析。结果 SF-36量表中各维度与性别无相关性;躯体功能、总健康、生命活力、社交功能4个维度分值与年龄有关;嗜睡组与非嗜睡组比较,此4个维度分值差异有统计学意义;躯体功能、躯体角色、躯体疼痛、总健康、生命活力、情感角色、精神健康7个维度分值分别与人体质量指数(body mass index,BMI)和夜间睡眠最低氧饱和度(lowest saturation,LSaO2)有关;躯体功能、躯体角色、总健康、生命活力、情感角色、精神健康6个维度分值分别与呼吸暂停低通气指数(apnea hypopnea index,AHI)有关。应用SF-36量表评价生活质量,表明OSAHS对患者生活质量的影响主要反映在躯体功能、总健康、生命活力3个维度而对患者的躯体疼痛和社交功能的影响相对较小。SF-36量表结果显示影响患者生命质量的综合因素主要是:EDS、BMI、LSaO2、AHI。结论年龄、BMI、EDS、LSaO2、AHI是影响OSAHS患者生活质量的因素,其中BMI、EDS、LSaO2、AHI对生活质量有负面影响。用SF-3 6量表对OSAHS患者进行评估可以比较全面地了解患者的生理、心理、社会等方面的功能状况,真实反映了疾病对患者的影响。应使用综合治疗,加强患者的心理支持,精神疏导,提高患者对疾病的认识水平及自我保护意识,提高OSAHS患者生活质量。更多还原

【Abstract】 Objective To investigate the effects of obstructive sleep apnea hypopnea syndrome(OSAHS) on the quality of life of the patients.Methods The quality of life was assessed with the Medical Outcomes study SF-36 Health Survey in 93 patients with OSAHS.Excessive Daytime sleepiness(EDS) was assessed with Epworth sleepiness scale(ESS).Pearson liner correlation were used for studying the association between each domain score of SF-36 Health Survey and patients information,PSG parameters Influences of age,gender,BMI(body mass index),EDS,and PSG parameters,EDS scores.Results Each domain of SF-36 had no significant difference in gender;four domains of SF-36 had correlation with age;five domains of SF-36 correlated with EDS;seven domains of SF-36 correlated between BMI and LSaO2(lowest Oxygen saturation);six domains of SF-36 correlated with AHI(apnea hypopnea index).The result of SF-36 instrument showed the results that the disease had the effect on three dimensionalities such as physical functioning,general health perceptions and vitality,but less influenced bodily pain and social functioning.It also showed that integrated infective factors included EDS,BMI,LSaO2,and AHI.Conclusion Age,BMI,EDS score,LSaO2,AHI have a significantly effect on the OSAHS patients.BMI,EDS score,LSaO2,AHI have a significant side effect on the OSAHS patients.Applying instruments of life quality to assessing of the OSAHS patients,we can know about the physical,emotional and social functions.It can factually reflect the effect of the disease and treatment,when comprehensive rehabilitation approach is applied,psychological support and psychiatric aberration must be stressed to make the patients look on the disease correctly,amend bad mood,cooperate with doctors actively.The knowledge of the disease and the consciousness of self health care must be improved to fetch favorable psychologic diathesis,and enhance the patients’qulity of life.更多还原