【摘要】 目的观察5-氨基酮戊酸光动力(ALA-PDT)疗法联合CO2激光治疗宫颈尖锐湿疣的疗效和复发率。方法将入选的38例患者随机分为两组,分别采用CO2激光及ALA-PDT联合CO2激光治疗,比较两组患者的疗效和复发率。结果治疗组的治愈率和治疗后3个月时复发率分别为84.20%和15.80%,对照组分别为36.80%和63.20%,其治愈率和治疗后3个月时的复发率比较,差异均有统计学意义(P均<0.05),两组患者均未发生不良反应。结论 ALA-PDT联合CO2激光治疗宫颈尖锐湿疣治愈率高,复发率低,患者依从性好。更多还原

【Abstract】 Objective To explore the efficacy of 5-aminolevulinic acid-photodynamic therapy combined with CO2 laser for the treatment of condyloma acuminata( CA) on cervix uteri. Methods Thirty-eight patients were divided into two groups randomly. One group were treated by CO2 laser only and the other by both ALA-PDT and CO2 laser. Results The cure rate and the recurrence rate in 3 months of the teatment group were 84. 20% and 15. 80% . And compared the cure rate and the recurrence of the two groups. Results The cure rate and the recurrence rate in 3 months of the teatment group were 84. 20% and 15. 80% . And in the control group were 36. 80% and 63. 20% respectively. The crue rate and the recurrence rate in 3 months of the two groups showed statistical significance( P < 0. 05) . There was no obvious adverse effect s in two groups. Conclusions The combination therapy of ALA-PDT with CO2 laser can raise the cure rate and reduce the recurrence of CA on cervix uteri,with good tolerance.更多还原