【摘要】 目的观察放射治疗配合紫杉醇化疗对食管癌的临床疗效。方法对173例食管癌患者根据不同的治疗方法分为单纯放射治疗组(单放组)和放射治疗同步化疗组(放化疗组)。单放组80例,放疗DT 65～70Gy;放化疗组93例,放疗同时化疗,紫杉醇每周60mg。两组均随访2年。结果放化疗组的近期效果好于单放组,有显着性差异(P<0.05)。单放组1、2年生存率为51.3%(41/80)、32.5%(26/80),同步放化组为87.19%(81/93)、68.8%(64/93),两组差异有显着性(P<0.05)。结论同步放化疗优于单纯放射治疗,可明显提高食管癌的疗效。更多还原

【Abstract】 Objective To study the effect of radiotherapy combined with paclitaxel on esophageal cancer.Method 173 cases of esophageal cancer were divided into conventional radiotherapy to a total of 65～70Gy;combined group with received the same radiotherapy as simple irradiation group plus chemotherapy with weekly paclitaxel.Both groups were followed for 2 years.Result The short-term results of radiotherapy combined with chemotherapy was better than that of radiotherapy alone.The survival rates in the combined group were thus much better than those in simple irradiation group(P<0.05).The one and two year survival rate in combined were 87%,68.8%.The one and two year survival rate in simple irradiation group were 51.3%,32.5%.The difference between these two groups was statistically(P<0.05).Conclusion Radiotherapy combined with chemotherapy were thus much better than those in simple irradiation group for advanced esophageal cancer.更多还原