【摘要】 目的:了解2005—2009年南京地区抗癫痫药的用药状况及变化趋势。方法:采用限定日剂量为指标,对南京地区2005—2009年临床应用的抗癫痫药的数据资料进行统计分析,对用药金额和药品限定日费用(DDC)进行排序。结果:南京地区抗癫痫药的总用药金额逐年增长。5年中抗癫痫药各类药物构成比中,丙戊酸钠金额占总金额的构成比超过了50%,在抗癫痫药市场中占主导地位。除了苯妥英钠、丙戊酸钠外,大多数抗癫痫药DDC波动较大。结论:抗癫痫药使用增长明显,传统抗癫痫药如丙戊酸钠、卡马西平仍占市场主导地位,新型抗抑郁药如托吡酯、拉莫三嗪等市场前景广阔。更多还原

【Abstract】 OBJECTIVE: To investigate the status quo and the tendency of clinical utilization of antiepileptic drugs in Nanjing area during the period 2005-2009.METHODS: By using the defined daily dose as index,the clinical utilization data of antiepileptic drugs in Nanjing area during 2005-2009 period were analyzed statistically and the consumption sum and defined daily cost(DDC) of which were ranked.RESULTS: The consumption sum of the antiepileptic drugs in Nanjing area increased year by year during 2005-2009.The consumption sum of Sodium Valproate accounted for more than 50% of that of total antiepileptic drugs,assuming a dominant place in the use of antiepileptic drugs.The DDC of most of antiepileptic drugs except those of phenytoin sodium and valproate sodium witnessed a sharp fluctuation.CONCLUSION: The consumption of antiepileptic drugs increased significantly.The old antiepileptic drugs such as Sodium valproate and Carbamazepine still took the lead and the future market for the new antiepileptic drugs such as Topiramate and Lamotrigine is potential.更多还原