【摘要】 消化系统恶性肿瘤是我国最常见的恶性肿瘤,是我国引起死亡最多的恶性肿瘤,主要包括食管癌、胃癌、结直肠癌、肝癌和胰腺癌等,发病率呈逐年上升趋势。恶性肿瘤的发生是遗传与环境因素共同作用、多种癌基因协同作用的结果。消化内镜检查和介入性诊治技术的开发与发展,提高了消化系统恶性肿瘤的检出率。肿瘤分子生物学研究对肿瘤的早期诊断和有效治疗,具有深远的影响。肿瘤防治的关键在于早期发现、早期诊断及早期治疗,是提高生存率的关键环节。内镜下黏膜切除术、内镜下黏膜下层剥离术等微创手术,已成为肿瘤早期治疗的发展趋势。更多还原

【Abstract】 Malignant tumors of digestive system including esophageal carcinomas,gastric carcinomas,colorectal carcinomas,hepatic carcinomas and pancreatic carcinomas are among the most common tumors with increasing prevalence and have the highest mortality in China.The occurrence of the malignant tumors Results from not only the interactive effects between heredity and environments but also synergistic effects of multiple oncogenes.The development and progress of endoscopic and invasive techniques facilitate the early detection of malignant tumors of digestive system.Molecular biology of tumors has profound impact on the early diagnosis and effective therapy of tumors.Early detection,diagnosis and therapy are the key points for the prevention and treatment of cancer and to increase the survival rate.Minimally invasive surgeries such as endoscopic mucosal resection and endoscopic submucosal dissection have become the popular methods to treat the early gastrointestinal tumors.更多还原