【摘要】 以室温下Zn/Me2SiCl2/DMA还原体系代替传统低温下(-78℃)有机锂试剂体系,高收率合成了4-乙酰巯基碘苯(6)和4-碘苯甲硫醚(7)。分别将二者与二茂铁乙炔偶联合成了二茂铁乙炔基苯硫酚衍生物1和2。研究了衍生物1和2的光谱和电化学性质,将其自组装到金电极上,获得了电活性较好的修饰电极。衍生物1修饰Au/GCE电极对芦丁有良好的催化电氧化作用,在生物/电化学传感器领域有潜在应用前景。更多还原

【Abstract】 Ferrocene-terminated phenylethynythiol derivatives 1 and 2 were prepared from S-acetyl-4-iodothiophenol(6) or 4-iodophenyl methyl sulfide(7) and ethynylferrocene via cross-coupling reactions.Compounds 6 and 7 were prepared in a good yield with Zn/Me2SiCl2/DMA(N,N-dimethylacet amide) reduction system at room temperature instead of traditional low temperature metal lithium system(-78 ℃).The spectral characteristics,electrochemical properties and self-assembly behaviors of the target compounds on Au modified glassy carbon electrodes(Au/GCE) were investigated.Compound 1 film coated Au/GCE has high electrocatalytic activity toward the oxidation of rutin and has potential applications as biosensor and electrochemical sensor.更多还原