【摘要】 合成了硫脲壳聚糖Co(Ⅱ)配合物,运用红外光谱、紫外光谱和差热热重分析对配合物进行了表征,研究了其对大肠杆菌和金黄色葡萄球菌的抑菌性能及与血清白蛋白(BSA)的相互作用。结果表明,硫脲壳聚糖能与Co(Ⅱ)发生配位反应而生成硫脲壳聚糖-Co(Ⅱ)配合物,该配合物的抑菌性能较壳聚糖和硫脲壳聚糖有显著提高,并能有规律地猝灭BSA的内源荧光。更多还原

【Abstract】 Thiourea-chitosan-Co(Ⅱ) complex was prepared and characterized by FT-IR,UV-Vis absorbance spectra and TG-DTA methods,the antibacterial activities of thiourea-chitosan-Co(Ⅱ) complex against E.coli and St.aureus were studied in vitro.Moreover,the interaction between thiourea-chitosan-Co(Ⅱ) complex and bovine serum albumin(BSA) was also studied by ultraviolet and fluorescence spectroscopies.The results confirm that the complex is formed,and the antibacterial activities of thiourea-chitosan-Co(Ⅱ) complex is obviously enhanced comparing to its ligands and the complex can quench the intrinsic fluorescence of BSA.更多还原