【摘要】 目的评价硝酸舍他康唑栓治疗外阴阴道假丝酵母菌病的疗效及安全性。方法采用随机双盲对照试验。治疗组及对照组各30例,分别外用硝酸舍他康唑栓300 mg和克霉唑栓500 mg,用药1或2次。停药后(7±1)d及28～35 d时进行观察。结果治疗组28例、对照组30例纳入分析,治疗组和对照组停药后(7±1)d临床有效率分别为89.29%,86.67%(P>0.05);用药结束后28～35 d时的临床有效率分别为81.48%6,6.67%(P>0.05);均未发生与药物相关的不良反应。结论硝酸舍他康唑栓治疗外阴阴道假丝酵母菌病有效,安全。更多还原

【Abstract】 Objective To evaluate the efficacy and safety of sertaconazole nitrate suppositories for treating vulvovaginal candidiasis.Methods A double-blind,randomized controlled trial was conducted.30 cases in both treatment group and control one were applied with sertaconazole nitrate suppositories and clotrimazole ones for 1-2 times,respectively.Patients were evaluated at day 7±1 and day 28-35 after ceasing medication.Results 28 cases in the medical trial group and 30 cases in control were evaluated;The clinical efficacy at day 7±1 were 89.29% in the test group and 86.67% in control group;and 81.48% versus 66.67% at day 28-35 after drug withdrawn,respectively.No treatment-related adverse events occurred in both groups.Conclusion This study suggests that sertaconazole nitrate suppositories are effective and safe for the treatment of vulvovaginal candidiasis.更多还原