【摘要】 目的:探讨低感染风险剖宫产产妇围术期预防性应用抗生素的最佳方案。方法:选择2007年1月～2010年12月在我院妇产科行剖宫产分娩的产妇544例,回顾性分析低感染风险子宫下段横切口剖宫产产妇围术期抗生素的不同用药方案。将其分为三组,A组190例,术前30 min一次给药,术后不再使用;B组180例,术前30 min开始给药,术后继续使用2 d;C组174例,手术结束后开始给药,共5 d。抗生素应用头孢唑林钠或林可霉素,均为静脉给药。比较三组产妇术后感染、术后病率、术后体温恢复正常的时间及住院天数。结果:544例产妇术后感染、术后病率分别为0.92%(5/544)和3.68%(20/544),三组产妇剖宫产术后感染发生率比较,差异无统计学意义(P>0.05),A组和B组产妇术后体温恢复正常的时间、术后病率及术后平均住院天数均分别显著低于C组[A组为(41.9±11.6)h、1.05%(2/190)、(4.8±1.1)d;B组为(41.1±16.5)h、1.11%(2/180)、(4.7±0.9)d;C组为(70.1±19.9)h、9.20%(16/174)、(5.9±1.1)d](均P<0.01)。但A、B组之间各项指标比较,差异无统计学意义(P>0.05)。结论:低感染风险产妇剖宫产术前30 min静脉使用抗生素能显著降低术后病率的发生,术后无需重复应用抗生素预防感染。更多还原

【Abstract】 Objective:To explore the optimum scheme used antibiotics of low infection risk cesarean puerpera perioperative prophylactic.Methods: 544 cases of pregnant women with puerpera of cesarean parturition in Department of Gynecology and Obstetrics in our hospital from January 2007 to December 2010,antibiotics different therapeutic schemes of low infection risk lower uterine segment crosscut mouth cesarean puerpera perioperative were retrospectively analyzed.They were divided into three groups,190 cases of group A,preoperative 30 min one for medicine,postoperative no longer used;180 cases of group B,preoperative 30 min began to medicine,and postoperative continue to use 2 d;174 cases of group C,began to medicine after the operation,5 d in all.Cefazolin sodium or lincomycin as antibiotics were given intravenously.Postoperative infection,postoperative morbidity,postoperative temperature returned to normal time and hospitalization days of three groups were compared.Results: Postoperative infection,the postoperative morbidity of 544 puerpera was 0.92%(5/544) and 3.68%(20/544) respectively,there were no significant differences of postoperative infection rate of three groups(P>0.05),postoperative temperature returned to normal time,postoperative morbidity and postoperative hospitalization days on average of group A and group B were significantly lower than group C [group A(41.9±11.6)h,1.05%(2/190),(4.8±1.1)d;group B(41.1±16.5) h,1.11%(2/180),(4.7±0.9)d;group C(70.1±19.9)h,9.20%(16/174),(5.9±1.1)d](all P<0.01).But there were no significant differences of each index of group A and group B(P>0.05).Conclusion: Low risk of infection puerpera intravenous antibiotics in preoperative 30 min cesarean delivery can significantly reduce the postoperative morbidity,it dosen’t need repeat antibiotics postoperative to prevent infection.更多还原