【摘要】 卵巢癌早期临床症状隐匿,多无自觉症状,患者确诊时多数已是临床晚期。目前由于缺乏卵巢癌早期诊断的有效方法,故寻找卵巢癌早期诊断的血清肿瘤标志物,对卵巢癌的预后和提高患者的生存质量率有着重要的意义。本文探讨了糖类抗原125(CA125)、人附睾蛋白4(HE4)、可溶性B7-H4(sB7-H4)、血清甲壳质酶蛋白40(YKL-40)的检测或联合检测的意义,对卵巢癌的筛查、诊断、指导治疗、估计预后等方面的研究进展进行综述。更多还原

【Abstract】 The clinical symptoms of early stage ovary cancer is dormant without any self-conscious symptoms by the pa-tients.Thus most patients are already in late stage of the disease when diagnosed.Currently there are no effective diagnosis methods of early stage ovary cancer.So it’s of great relevance to the prognosis and life quality of patients to detect cancer markers of ovary cancer in blood serum.This article investigates the significance of detection or combined detection of car-bohydrate antigen 125(CA 125),human epididymis protein(HE4),soluble B7-H4 and YKL-40.In addition,literature on the research progress of ovary cancer screening,diagnosis,treatment guideline and prognosis estimation have also been re-viewed.更多还原