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阿尔兹海默病与血管性痴呆的诊疗对比

Comparative studies on diagnosis and curative effect for Alzheimer’s disease and vascular dementia

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【作者】 雷建明王文尚方玲杨职黎朝茂江先娣

【Author】 LEI Jianming1,WANG Wenshang2,FANG Ling1,YANG Zhi1,LI Chsomao1,JIANG Xiandi1(1.Department of Neurology,People’s Hospital of Maoming City in Guangdong Province,Maoming 525000,China;2.Department of Radiology,People’s Hospital of Maoming City in Guangdong Province,Maoming 525000,China

【机构】 广东省茂名市人民医院神经内科广东省茂名市人民医院放射科

【摘要】 目的:探讨阿尔兹海默病与血管性痴呆的诊断方法和治疗效果。方法:选取我院2006~2010年收治的阿尔兹海默病和血管性痴呆患者,观察比较其诊断指标和治疗效果。结果:AD和VaD患者MMSE-R评分无显著差异;AD组和VaD组脑电图异常率有统计学意义(P<0.01),AD组脑电图异常率低于VaD组;AD与VaD组患者血浆Hcy、VitB12和ChE差异有统计学意义(P<0.05);AD组与VaD组认知功能、记忆功能和社会行为能力改善比较差异有统计学意义(P<0.05),VaD组改善均好于AD组。结论:通过临床症状和生化检查在一定程度上能够鉴别AD和VaD患者,同时针对二者不同的病因和发病机制,采取相应的治疗措施有一定的效果,值得临床借鉴。

【Abstract】 Objective:To explore the diagnosis and curative effect of AD and VaD.Methods:Retrospective analysis of the patient’s dates from 2006 to 2010 in our hospital,to observe diagnostic indexes and curative effect.Results:MMSE-R for AD and VaD was not different significantly.EEG for AD and VaD were statistical different significantly(P<0.01);Hcy,VitB12 and ChE for AD and VaD were statistical different significantly;Cognitive function、memory function、ability and social behaviors were statistical different significantly(P<0.05),curative effect of VaD was better than AD.Conclusion:Symptom and biochemistry can be used for differential diagnosis.Taking effective treatment according to pathogenesis should be good for AD and VaD and be used for reference.

  • 【文献出处】 中国医药导报 ,China Medical Herald , 编辑部邮箱 ,2011年20期
  • 【分类号】R749.16
  • 【被引频次】5
  • 【下载频次】496
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