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绝经后骨质疏松症的临床治疗进展

The progress of clinical treatment of postmenopausal osteoporosis

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【作者】 黄立莉洪文王立源何涓吕小华王碧云

【Author】 HUANG Lili1,HONG Wen2,WANG Liyuan3,HE Juan1,LU Xiaohua4,WANG Biyun5 1.Department of Gynecology,Dongsheng Hospital of Guangzhou City,Guangzhou 510120,China;2.Department Traditional Chinese Medicine,Dongsheng Hospital of Guangzhou City,Guangzhou 510120,China;3.Department of Radiology,Dongsheng Hospital of Guangzhou City,Guangzhou 510120,China;4.Pharmacology Teaching and Research Section of Guangdong Medical College,Zhanjiang 524001,China;5.Medical Examination Center of the Affiliated Hospital of Guangdong Medical College,Zhanjiang 524001,China

【机构】 广州市东升医院妇科广州市东升医院中医科广州市东升医院放射科广东医学院药理教研室广东医学院附属医院体检中心

【摘要】 绝经后骨质疏松(postmenopausal osteoporosis)是绝经后妇女的常见病及多发病,指绝经后妇女由于卵巢功能衰退,雌激素水平下降,继发甲状旁腺功能亢进,降钙素分泌不足,从而导致破骨细胞的骨吸收大于成骨细胞的骨形成,出现以低骨量和骨组织的显微结构退行性变为其特征,临床表现为骨脆性和骨折易感性增加的一种代谢性疾病。本文通过对绝经后骨质疏松的临床治疗作相关的回顾和综述,探讨绝经后骨质疏松症的临床治疗效果以及研究方向。

【Abstract】 Postmenopausal osteoporosis is a disease of common and frequently-occurring in postmenopausal women,refers to ovarian function decline due to a drop in estrogen levels,following made parathyroid function with hyperparathyroidism,drop calcitonin secretion insufficient,which lead to osteoclasts′ absorption is greater than osteoblasts in bone formation,characterized by low bone mass,degenerative of microstructure of osseous tissue,the clinical manifestations of the fragility and fracture predisposition to increase.Through to review and summary the clinical treatment of postmenopausal osteoporosis in this paper,exploring its clinical treatment effect and research directions.

  • 【文献出处】 中国医药导报 ,China Medical Herald , 编辑部邮箱 ,2011年18期
  • 【分类号】R580
  • 【被引频次】76
  • 【下载频次】1099
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