【摘要】 目的:了解原发性十二指肠肿瘤的手术治疗方法,探讨原发性十二指肠肿瘤的术式选择。方法:对56例原发性十二指肠恶性肿瘤患者实施标准胰十二指肠切除术(A组,26例),肿瘤局部切除术(B组,14例)和旁路手术(C组,16例),观察三组患者的1、3、5年的生存率,并进行对比。结果:A组26例患者1年生存者22例,占84.6%,3年生存者16例,占61.5%,5年生存者9例,占34.6%;B组14例患者1年生存者8例,占57.1%,3年生存者5例,占35.7%,5年生存者2例,占14.3%;C组16例患者1年生存者2例,占12.5%,无3、5年生存者。A组术后1、3、5年生存率与B组比较,差异有高度统计学意义(χ2=6.27、4.23、3.92,P<0.01);A组术后1、3、5年生存率与C组比较,差异有高度统计学意义(χ2=11.35、8.24、6.81,P<0.01);B组术后1、3、5年生存率与C组比较,差异有高度统计学意义(χ2=5.02、13.42、4.23,P<0.01)。结论:手术治疗原发性十二指肠肿瘤的首选术式是标准胰十二指肠切除术,其次为肿瘤局部切除术,而对于晚期原发性十二指肠肿瘤患者来说,使用旁路手术对改善患者预后有积极意义。更多还原

【Abstract】 Objective: To acquaint the surgery method and explore the choosing operatic method of primary duodenal tumors.Methods: 56 cases with primary duodenal tumors were treated by standard pancreaticoduodenectomy(group A,26 cases),local excision(group B,14 cases) and bypass surgery(group C,16 cases),and to observe the its 1,3,5-year survival rates,and compared.Results: Group A of 26 cases 1 year survival in 22 cases,accounting for 84.6%,3-year survival in 16 cases,accounting for 61.5%,5-year survival in 9 cases,accounting for 34.6%;group B 1-year survival of 14 patients,8 cases 57.1%,3-year survival of 5 cases,accounting for 35.7%,5-year survival in 2 cases,accounting for 14.3%;group C 1 year survival of 16 cases in 2 cases,accounting for 12.5%,no 3-year survivors.Group A after 1,3,5-year survival rate compared with the group B,there was significant differences(χ2=6.27,4.23,3.92,P<0.01);group A after 1,3,5-year survival rate compared with the group C(χ2=11.35,8.24,6.81,P<0.01);group B 1,3,5-year survival rate compared with the group C,there were significant differences(χ2=5.02,13.42,4.23,P<0.01).Conclusion: The standard pancreaticoduodenectomy is the best treatment of the primary duodenal tumors,the secondly is the local excision,but the bypass surgery has a positive means for the terminal primary duodenal tumors.更多还原