【摘要】 目的:探讨重组人干扰素α-2b凝胶治疗慢性宫颈炎的治疗效果及其原因,以揭示运用重组人干扰素α-2b凝胶治疗该疾病的可行性。方法:通过对2005年5月～2010年6月来广州市东升医院就诊的268例20~50岁患有不同程度慢性宫颈炎的女性(轻度96例,中度120例,重度52例)应用重组人干扰素α-2b凝胶进行1~3个月的治疗效果观察。结果:用药治疗后1个月复查,其有效率为63.1%,用药3个月后复查,其有效率为81.7%,用药3个月后与1个月后有效率比较,差异有统计学意义(P<0.05)。轻度及中度糜烂疗效较好,重度糜烂疗效较差。结论:重组人干扰素α-2b凝胶治疗慢性宫颈炎疗效是明显的,对于重度糜烂可以增加疗程以提高疗效。更多还原

【Abstract】 Objective: To investigate the therapeutic efficacy of using the recombinant human interferon α-2b gel as a treatment to chronic cervicitis and hence to reveal the feasibility of this kind of treatment method.Methods: One to three months treatment of using recombinant human interferon α-2b gel and consequent observation to the 268 patients(ages 20-50) suffered from different severities of chronic cervicitis(96 cases of mild severity,120 of moderate and 52 of severe) were carried out during May 2005 to June 2010 in Guangzhou Dongsheng Hospital.Results: The short-term effective rate was 63.1% according to the follow-up examination conducted one month after the treatment and the rate climbs to 81.7% three months after the treatment,there was a significant difference both of them(P<0.05),which indicated that the treatment was relatively effective as to the cases with mild to moderate symptoms but not with severe ones.Conclusion: The therapeutic effectiveness of the treatment of using the recombinant human interferon α-2b gel for chronic cervicitis is significant and the treatment should be elongated for the cases with severe symptoms to achieve a satisfactory therapeutic effectiveness.更多还原