【摘要】 目的探讨0.1%盐酸左旋布比卡因硬膜外给药用于可行走镇痛分娩的临床效果。方法根据个人意愿,将2010年2月至2011年3月在我院住院的足月妊娠、单胎、头位、初产200例分为实验组和对照组,每组各100例,实验两组产妇产程、镇痛前后疼痛变化、分娩方式、缩宫素使用情况及新生儿出生1分钟Apgar评分情况。结果实验组总产程缩短,尤其是第一产程活跃期明显短于对照组,差异有统计学意义(P<0.01);实验组镇痛后疼痛程度明显减轻,与镇痛前比较差异有统计学意义(P<0.01);剖宫产率两组比较差异有统计学意义(P<0.05);实验组和对照组缩宫素使用情况及新生儿1 min Apgar评分比较,两组差异无统计学意义(P>0.05)。结论 0.1%盐酸左旋布比卡因硬膜外镇痛用于分娩镇痛安全有效,能缩短产程,减轻疼痛,降低剖宫产率,对新生儿无影响。更多还原

【Abstract】 Objective To investigate the therapeutic effect of 0.1% levobupivacaine HCl on ambulatory or walking epidural analgesia in labor.Methods Based on the individual intention,200 hospitalized cases from February 2010 to March 2011 of full-term,singleton pregnancy,head delivery and primiparity,were divided into the observation group and the control group equally,which were then observed on stages of labor,changes of pain before and after analgesia,ways of delivery,use of oxytocin and the Apgar scores of newborns at one minute.Results The total stage of labor of observation groups was shorter than the control group,especially the active phase of the first stage,and the differences were statistically significant(P<0.01);the pain after analgesia of experimental groups was less,which was significantly contrast with pain before analgesia(P<0.01);the difference of cesarean section rate between the two groups was significant(P<0.05);and the differences in use of oxytocin and newborns′ Apgar scores at one minute were not statistically significant(P>0.05).Conclusion 0.1% levobupivacaine HCl using in Epidural Analgesia is safe and effective for labor analgesia that it can shorten the stage of labor,reduce pain,lower the cesarean section rate,and has no effect on newborns.更多还原