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β受体阻断剂在慢性心衰中作用的基础机制
The Basic Mechanism of Beta-blocker in Chronic Heart Failure
【摘要】 心力衰竭是很多心血管疾病的最终阶段,也是常见的致死原因之一。心力衰竭时起代偿作用的交感神经系统的持续兴奋是导致心力衰竭恶化的一个重要原因。近年来,众多临床试验证实β受体阻断剂类药物对心力衰竭有良好的治疗作用,β受体阻断剂能通过慢性抑制交感神经的兴奋,改善心力衰竭患者心功能,从而减少患者病死率,增加生存率。
【Abstract】 Heart failure is the final phase for many cardiovascular diseases,one of the common fatal causes as well.One important reason of heart failure deterioration is the sustained excitement of sympathetic nervous system which is a compensatory mechanism in heart failure.In recent years,evidence has been accumulated on the beneficial actions of beta-blockers in patients with heart failure.The effect of beta-blocker in chronic inhibition of sympathetic nervous system can improve cardiac function of heart failure patients,reduce mortality and increase survival rates.
- 【文献出处】 医学综述 ,Medical Recapitulate , 编辑部邮箱 ,2011年10期
- 【分类号】R541.6
- 【被引频次】10
- 【下载频次】573