【摘要】 目的分析弥漫性轴索损失（DAI）的MRI表现,探讨磁敏感加权成像（SWI）对DAI的诊断价值。方法回顾性分析30例临床诊断为DAI患者的MRI图像,比较病灶在各序列的显示率,并分析其信号特征及分布部位。结果 T₁WI序列显示率较低,其次为T₂WI序列,显示者T₁WI为低信号,T₂WI为高信号,FLAIR序列敏感性较高,显示者为片状、斑片状高信号,病灶越小显示越不敏感,SWI序列显示病灶更多、更敏感,病灶主要分布在皮髓质交界区、基底节、胼胝体、脑干及小脑上脚等,呈散在针尖状、小片状或片状显著低信号。结论相比常规MR序列,SWI序列对DAI病灶检出率更高,可为DAI作出准确诊断,对临床怀疑为DAI患者,SWI序列可作为常规MR序列的重要补充。更多还原

【Abstract】 Objective To investigate the value of SWI sequence in diagnosis of DAI by analyzing the MRI images of DAI. Methods The MRI data of 30 cases with DAI diagnosed by clinic were analyzed retrospectively.The signal intensity features and detection rate of lesions were compared in all sequences.Results SE T₁WI sequence had the lowest sensitivity,secondly was T₂WI sequence.DAI showed as long T₁ long T₂ signal.Some lesions could be detected with FLAIR,appearing as nodular or patchy hyperintensity. More lesions were detected with SWI sequence than with other sequences.DAI lesions mainly located in the junctional zone of cortex and medulla,basal ganglia,corpus callosum,brain stem and cerebellum.It appeared as needle tip,mottling,nodular hypointensity in SWI sequence.Conclusion SWI can detect more lesions in cases with DAI than other sequences.It can be an additional sequence in MRI examination for the patients suspicioused with DAI.更多还原