【摘要】 为了研究肿节风全草中倍半萜类化学成分,利用硅胶柱色谱、凝胶柱色谱、ODS柱色谱及制备液相色谱等分离技术从肿节风70%乙醇提取物的正丁醇和乙酸乙酯萃取部分分离得到4个倍半萜内酯类成分,根据化合物的光谱数据分别鉴定为4α-hydroxy-5αH-lindan-8(9)-en-8,12-olide(1)、chloranthalactone E(2)、8β,9α-dihydroxylindan-(5),7(1)-ieb-8α,12-olide(3)和chloranoside A(4)。其中化合物1为新化合物。更多还原

【Abstract】 To study the sesquiterpenoid constituents in the whole plant of Sarcandra glabra,silical column chromatography,Sephadex LH-20,reverse phase ODS column chromatography and preparative HPLC were used to isolate 70% EtOH extract of Sarcandra glabra.The structures were elucidated based on spectroscopic data(HR-ESI-MS,1H NMR,13C NMR,HSQC,HMBC and NOESY).Four sesquiterpenoids were obtained and identified as 4α-hydroxy-5αH-lindan-8(9)-en-8,12-olide(1),chloranthalactone E(2),8β,9α-dihydroxylindan-(5),7(1)-ieb-8α,12-olide(3) and chloranoside A(4),respectively.Compound 1 is a new sesquiterpene lacone.更多还原