节点文献
法-林效应机理详释
Fahraeus-Lindqvist Effect Mechanism Explained in Eetail
【摘要】 研究目的是揭示其根本机理,并通俗阐明,以适应医学群体的需要。论文在阐明何谓法-林效应、红细胞向轴集中等概念基础上揭示出:法-林效应的根本机理有两个:其一,红细胞向轴集中,从而产生管壁血浆层。因为血浆层的存在,导致在侧支管口有较多的血浆成分流入支管。即所谓血浆撇取效应。又因为侧支管存在血浆层导致血液二相流的形成。侧支管越小血浆撇取效用越明显,二相流导致的血液表观黏度越低。其二,管口效应。简而言之就是流到分支管的红细胞长轴与侧支管管口段轴的夹角越小就越容易流入支管。当然侧支管越小红细胞越难流入。论文还阐明了逆法-林效应的机理。
【Abstract】 This paper aims to reveal and clarify the fundamental mechanism of Fahraeus-Lindgvist effect so as to adapt to the need of the medical group.On the basis of expounding the definitions of the concept of fundamental mechanism of Fahraeus-Lindgvist effect and the red cells’ concentrating to shaft,it reveals that Fahraeus-Lindgvist effect contains two fundamental mechanisms.One is the producing of plasma layer of venous wall resulting from the red cells’ concentrating to shaft.The existence of plasma layers results in many plasma components in the sides of the branch pipe orifices flowing to the branch pipes,that is the so-called blood plasma skim effect.Also due to the formation of the two-phase flow resulting from the plasma layer in the side branch pipes,the blood plasma skim effect in the branch pipes becomes more evident and the blood viscosity caused by two-phase flow turns even lower.The other is the orifice effect of pipe.In brief,the smaller of the angle between the axis of the red cells flowing into the the branch pipe and the opening section of shaft in the side branch pipe,the easier the red cells will flow into the the branch pipes.It is certain that the smaller the side branch pipes are,the more difficult the red cells will flow into them.In addition,the paper also expounds the converse Fahraeus-Lindgvist effect mechanism.
【Key words】 Fahraeus-Lindqvist Effect; the converse of Fahraeus-Lindqvist Effect; blood plasma skim effect; two-phase flow model; orifice effect of pipe;
- 【文献出处】 中国医学物理学杂志 ,Chinese Journal of Medical Physics , 编辑部邮箱 ,2011年06期
- 【分类号】R331
- 【被引频次】2
- 【下载频次】138