【摘要】 目的:探索治疗偏头痛伴有焦虑和/或抑郁患者的有效方法,以及研究联合应用抗焦虑/抑郁药物的疗效。方法:将80例偏头痛伴有焦虑和/或抑郁的患者随机分为2组。治疗组40例,用黛力新+非甾体抗炎药(主要成分为对乙酰氨基酚)治疗;对照组40例,单用非甾体抗炎药治疗,并进行随机单盲对照研究。同时用汉密尔顿焦虑量表评分(HAMA)和汉密尔顿抑郁量表评分(HAMD),经抗焦虑和/或抗抑郁治疗前及治疗后(第4、8周)进行评估。结果:治疗组患者头痛发作次数显著减少或消失,头痛程度显著减轻或消失,头痛发作持续时间缩短,同时能显著减少(HAMA)(第4、8周均P<0.01)和(HAMD)(第4、8周均P<0.01)。结论:对偏头痛伴有焦虑和/或抑郁的患者,除对症治疗外,联用黛力新可提高疗效。更多还原

【Abstract】 Objective:To explore the treatment of migraine associated with anxiety and/or effective way to depression and anxiety combined research/depression,the effect of drugs.Methods:80 patients with migraine associated with anxiety and/or depression were randomly divided into 2 groups.40 patients treated with Deanxit+non-steroidal anti-inflammatory drugs(mainly paracetamol) treatment,40 patients in control group,single-use non-steroidal anti-inflammatory drug treatment,and randomized single blind controlled study.At the same time with the Hamilton anxiety scale score(HAMA) and Hamilton depression scale(HAMD),by anxiety and/or antidepressant therapy before and after treatment(the first 4,8 weeks) for evaluation.Results:The treatment group were headache,seizure frequency was significantly decreased or disappeared,headache level was significantly reduced or disappeared,headache duration,also significantly reduced(HAMA)(4 weeks,8 weeks,all P<0.01) and(HAMD)(4 weeks,8 weeks,all P<0.01).Conclusion:Migraine associated with anxiety and/or depressed patients,in addition to symptomatic treatment,combined with Deanxit may improve the outcome.更多还原