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正交试验优选镰形棘豆总黄酮活性炭脱色工艺

Optimization of decolorization technology of the Oxytropis falcata total flavones with active carbon by orthogonal experiment

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【作者】 杜青云洪佳妮李茂星陈锦珊

【Author】 DU Qing-yun~(1,2),HONG Jia-ni~(1,2),LI Mao-xing~3,CHEN Jin-shan~2(1.Department of Pharmacy,Medical College of Xiamen University, Xiamen 361005,China;2.Department of Pharmacy,the 175th Hospital of PLA,Zhangzhou 363000,China;3.Department of Pharmacy, Lanzhou General Hospital of PLA,Lanzhou 730050,China)

【机构】 厦门大学医学院药学系解放军第175医院药剂科兰州军区兰州总医院药材科

【摘要】 目的优选镰形棘豆总黄酮活性炭脱色工艺。方法以温度、时间和活性炭用量为考察因素,脱色液颜色、260~420nm紫外吸收情况和总黄酮含量为考察指标,采用正交试验法探究最佳脱色条件。结果脱色最佳工艺为在40℃下,加入1%活性炭,搅拌5min。结论该脱色工艺可行,既能达到脱色效果,又能保留有效成分。

【Abstract】 Objective To optimize the decolorization technology of Oxytropis falcata total flavones with active carbon.Methonds Temperature,stirring time and the content of active carbon were used as the orthogonal experiment factors.The colour of filtrate, the ultraviolet absorption between 260 nm to 420 nm and the content of total flavones were set as the indexes to investigate the optimal decolorization technology.Results The optimal decolorization technology was achieved under the condition as 40℃,stirring 5 min with 1%active carbon.Conclusion The decolorization technology is feasible which had good decolorization result and could hold effective ingredient.

【基金】 全军医药卫生“十一五”课题面上项目(06MB95);南京军区医药卫生科研课题(06MA-95)
  • 【文献出处】 药学实践杂志 ,Journal of Pharmaceutical Practice , 编辑部邮箱 ,2011年02期
  • 【分类号】R283
  • 【被引频次】7
  • 【下载频次】429
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