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2型糖尿病肾病肾功能不全与抑郁关系研究
The Relationship between Depression and the Severity of Renal Insufficiency in Patients with Type 2 Diabetic Nephropathy
【摘要】 目的:观察2型糖尿病肾病患者抑郁障碍状况与肾功能不全的关系。方法:对130例2型糖尿病肾病患者检测肾功能,根据血清肌酐值分为肾功能正常组、肾功能不全代偿组、肾功能不全失代偿组,同时采用zung抑郁自评量表(SDS)测试评分,分析SDS评分与肾功能不全严重程度的关系。结果:糖尿病肾病患者肾功能正常55例,肾功能不全代偿组35例,失代偿组40例,SDS标准评分别为:(52.55±14.20)分、(58.11±12.28)分、(64.22±10.99)分,存在显著性差异(P<0.01)。糖尿病肾病患者抑郁101例(77.7%),SDS评分与糖尿病肾病肾功能肌酐水平成正相关(r=0.369,P<0.01)。结论:2型糖尿病肾病患者存在不同程度的抑郁障碍,抑郁程度与肾功能肌酐水平相关。
【Abstract】 Objective:To investigate the relationship between depression and the severity of renal insufficiency in patients with type 2 diabetic nephropathy.Methods:130 patients with type 2 diabetic nephropathy were evaluated with Self-rating Depression Scale(SDS).The relationship between the SDS score and the level of creatinine was assessed.Results:The patients with normal renal function in type 2 diabetic nephropathy was 55,renal function in compensatory state was 35,and renal failure was 40.The SDS score was(52.55±14.20)、(58.11±12.28)、(64.22±10.99),respectively.They were significantly differences(P<0.01).The rate of depression was 77.7% in patients with type 2 diabetic nephropathy.The SDS score had significantly positive correlation to the level of creatinine(r=0.369,P<0.01).Conclusion:There were high frequencies of depression in patients with type 2 diabetic nephropathy.
- 【文献出处】 医学理论与实践 ,The Journal of Medical Theory and Practice , 编辑部邮箱 ,2011年22期
- 【分类号】R587.2
- 【被引频次】2
- 【下载频次】80