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消渴丸致低血糖反应文献分析

Literature Analysis of Low Blood Sugar Reactions Caused By Xiaoke Pill

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【作者】 郭美华马满玲董慧贤李希娜

【Author】 Guo Meihua,Ma Manling,Dong Huixian,Li Xina Department of Pharmacy,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,China

【机构】 哈尔滨医科大学附属第一医院药学部

【摘要】 目的:了解消渴丸所致低血糖反应发生的情况并分析相关因素,为临床合理用药提供参考。方法:对消渴丸所致的207例低血糖反应文献进行分类统计与分析。结果:男女比例为1.3:1,76.3%的病例为老年人,50.2%的病例不规范用药,17.9%单独用药,54.1%联合用药,临床类型以低血糖昏迷为主(80.2%),89.9%病例治愈,21例(11.1%)病例转归不良(死亡17例)。结论:消渴丸可引起较为严重的低血糖反应,甚至可致死亡,使用时须慎重考虑年龄、用法用量等相关因素,做到合理用药,减少低血糖反应的发生。

【Abstract】 Objective:To learn the cases of low blood sugar reactions caused by Xiaoke Pill and analyze their relevant factors to provide references for the clinical use of drugs.Method:207 cases of Xiaoke Pill-induced low blood sugar reactions were statistically analyzed.Result:The male to female ratio was 1.3:1 and 76.3%of the cases were the elderly. 50.2%of the patients had non-standard use of drugs,17.9%,single drug and 54.1%had their combined use of drugs.The clinical types of the cases were mainly hypoglycemic coma(80.2%),89.9%of cases were cured,and 21 cases(11.1%) showed adverse outcome(death in 17 cases).Conclusion:Xiaoke Pill could cause more severe low blood sugar reactions,and even cause death;therefore,the age,usage,dosage and other factors,must be carefully considered in order to use it rationally and reduce the incidence of hypoglycemia when it is used.

【基金】 紫禁城国际药师论坛科研课题项目
  • 【文献出处】 药物流行病学杂志 ,Chinese Journal of Pharmacoepidemiology , 编辑部邮箱 ,2011年12期
  • 【分类号】R286;R595.3
  • 【被引频次】4
  • 【下载频次】124
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