【摘要】 目的探讨血浆组织因子途径抑制物(TFPI)水平与肺血栓栓塞症(PTE)的关系。方法选择PTE患者35例,健康对照组34名。采用全自动血凝分析仪检测TFPI的活性、酶联免疫吸附试验(ELISA)法进行TFPI抗原测定。结果 PTE患者血浆TFPI活性、截短TFPI抗原、总TFPI抗原和全长TFPI抗原与对照组比较,差异均无统计学意义(P>0.05)。结论 PTE患者血浆TFPI活性及其抗原活性可能与PTE发病无明显相关性。更多还原

【Abstract】 Objective To investigate the relationship between altered levels of tissue factor pathway inhibitor (TFPI) and pulmonary thromboemlism (PTE).Methods Thirty five cases of PTE and 34 normal controls were examined for TFPI activity and TFPI antigen level using ELISA and one-stage clotting assay.Results The levels of TFPI:Ac,tr-TFPI:Ag,t-TFPI:Ag and f-TFPI:Ag were not statistically different between PTE patients and normal controls (P> 0.05).Conclusion The activity and antigen of TFPI may not be correlated with development of PTE.更多还原