【摘要】 目的:探讨阿托伐他汀钙(立普妥)对脑梗死患者颈动脉斑块及血清超敏C反应蛋白的影响。方法:对70例脑梗死合并颈动脉斑块患者在神经内科常规治疗基础上给予阿托伐他汀钙联合治疗,治疗前、后检测其血清超敏C反应蛋白水平,采用彩超检查颈动脉内-中膜厚度(IMT)及颈动脉斑块数量。结果:治疗前、后比较,患者颈动脉内-中膜厚度有显著改善,差异有统计学意义(P<0.05),超敏C反应蛋白水平明显下降。结论:阿托伐他汀钙可显著稳定动脉粥样硬化斑块,有利于抑制炎症反应。更多还原

【Abstract】 Objective:to study the influence of atorvastatin(lipitor) for patients with cerebral infarction with carotid artery atherosclerosis and high-sensitivity c-reactive protein.Methods:70 cases of cerebral infarction patients complicated with carotid artery atherosclerosis and therapeutic alliance of atorvastatin was given on the basis of conventional therapy.At the beginning and the end of the treatment,testing the high-sensitivity c-reactive protein level,using color dopplar ultrasound examination carotid intima-media thickness(IMT) and the numbers of carotid artery atherosclerosis.Results:after treatment,patients were compared with pretherapy,carotid intima-media thickness has improved significantly,the difference was statistically significant(P<0.05),high-sensitivity c-reactive protein value obviously decreased.Conclusion:atorvastatin can significantly atherosclerotic plaque stabilization,be helpful for inhibiting inflammation.更多还原