【摘要】 目的探讨OSA-18量表评价儿童睡眠呼吸紊乱严重程度的价值。方法我科收治的疑似阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)儿童患者160例,均行多道睡眠描记术(polysomnography,PSG)监测。采用OSA-18评估患儿的生活质量。分析确诊为OSAHS患儿的呼吸暂停低通气指数(apnea hypopnea index,AHI)和最低血氧饱和度(lowest oxygen saturation,LSaO2)与OSA-18评分的相关性。结果确诊OSAHS患者123例,单纯鼾症37例。OSAHS患者的OSA-18评分与AHI及LSaO2的相关系数分别为0.615和-0.496,P<0.05。单纯鼾症及轻中度OSAHS患者各组间OSA-18中位数差异有统计学意义(P<0.05);重度OSAHS患者OSA-18中位数为91.0,高于单纯鼾症及轻、中度OSAHS患者(OSA-18评分依次为64.0、76.0和87.0,P<0.05)。以LSaO2为依据对OSAHS患者进行分组,发现无低氧血症组及轻、中度低氧血症患者各组间OSA-18中位数差异有统计学意义(P<0.05),重度低氧血症患者OSA-18中位数为93.0,高于无低氧血症组及轻、中度低氧血症患者(OSA-18评分依次为69.0、81.0和89.0,P<0.05)。结论 OSA-18评分与PSG存在相关关系,在不同程度睡眠呼吸紊乱中有差异,可作为临床诊断儿童OSAHS的评价指标。更多还原

【Abstract】 Objective To investigate the value of OSA-18 questionnaire in evaluating the extent of severity of pediatric sleep-disordered breathing(SDB).Methods Polysomnography(PSG)and OSA-18 was performed in 160 suspected pediatric obstructive sleep apnea hypopnea syndrome(OSAHS)patients.The correlations between apnea hypopnea index(AHI)and lowest oxygen saturation(LSaO2)and OSA-18 score were analyzed in patients who were finally diagnosed as OSAHS.Results One hundred and twenty-seven patients were finally diagnosed as OSAHS and 37 cases as simple snoring.The correlation coefficients of OSA-18 score with AHI and LSaO2 were 0.615 and-0.496 respectively(P<0.05).Significant difference in median of OSA-18 score was observed among simple snoring,mild OSAHS and moderate OSAHS group.The median of OSA-18 score in severe OSAHS was 91.0,which was higher than that in simple snoring,mild OSAHS and moderate OSAHS group(64.0,76.0 and 87.0 by turns)(P<0.05).All OSAHS patients were divided into groups according to LSaO2.The difference of median of OSA-18 score among non-,mild and moderate hypoxemia patients was obvious(P<0.05).The median of OSA-18 score in severe hypoxemia was 93.0,which was higher than that in non-,mild and moderate hypoxemia patients(69.0,81.0 and 89.0 by turns)(P<0.05).Conclusions OSA-18 was correlated with PSG,and difference was observed in different extent of sleep-disordered breathing.OSA-18 was helpful for the diagnosis of pediatric OSAHS.更多还原