【摘要】 目的应用心脏磁共振成像检测青壮年肥胖者心脏结构及功能的改变。方法对青壮年肥胖者15例和16例健康志愿者(对照组),应用1.5T超导型磁共振扫描仪(Sonata,Siemens),体部相控阵及表面线圈,胸前导联回顾性心电门控,采集左心室长轴两腔位、四腔位、三腔位及短轴位动态图像,采用TurboFlash2D电影序列行左室短轴电影成像,用argus软件mass analysis分别描记左室心内、外膜界面,自动画出左室容积-时间变化曲线,测得左心室舒张末期容积参数和功能参数,并对正常志愿者组与肥胖者组临床资料及左心室功能数据结果进行比较。结果肥胖组同健康志愿者组比较,左室舒张末期容积(EDV)、收缩末期容积(ESV)、每搏量(SV)、心输出量(CO)、心肌质量(MM),以及左室高峰射血率(PER)、高峰射血时间(TPER)、高峰充盈率(PFR)、高峰充盈时间(TPFR)、室壁增厚率(TN),差异均有统计学意义(P<0.05),射血分数(EF)及第一层增厚率(P>0.05),无统计学差异。结论肥胖可引起青壮年人群心脏结构改变,使青壮年人群心脏舒张功能下降;CMR还可以较早检测肥胖者心脏结构和功能的异常。更多还原

【Abstract】 Objective Application of cardiac magnetic resonance imaging detection of young obese cardiac structure and function of the change.Methods 15 cases of young adults obese and 24 healthy volunteers(control group),the application 1.5T superconducting magnetic resonance scanner(Sonata,Siemens),and phased array body surface coil,ECG precordial gated,collecting bits left ventricular long axis two-chamber,four-chamber position,three-chamber and short axis dynamic digital images,using Turbo fast steady-state precession acquisition(FIESTA) 2D imaging sequence line left ventricular movies,software,mass analysis with Argus left ventricular heart tracings,respectively,the outer membrane interface,automatically draw the left ventricular volume-time curve,the measured parameters of left ventricular end-diastolic volume and function parameters,and the normal group and the obese group of volunteers,clinical data and left ventricular function Data were compared.Results The obese group compared with healthy volunteers,left ventricular end-diastolic volume(EDV),end-systolic volume(ESV),stroke volume(SV),cardiac output(CO),myocardial mass(MM),and left ventricular peak ejection rate(PER),peak ejection time(TPER),peak filling rate(PFR),peak filling time(TPFR),wall thickening(TN),the differences were statistically significant(P<0.05),ejection fraction(EF) and third layer thickness ratio(P>0.05) no significant difference.Conclusions Obesity can cause structural changes in the heart of young people to make young people diastolic dysfunction;CMR can detect early obesity abnormal cardiac structure and function.更多还原