【摘要】 目的探讨水通道蛋白3(AQP-3)在鼻息肉组织中的表达。方法对50例下鼻甲组织和137例鼻息肉组织(水肿型78例,腺囊肿型32例,纤维型27例),应用免疫组织化学技术检测AQP-3在下鼻甲黏膜组织和不同组织分型鼻息肉组织中的表达。结果在腺体、血管及血窦内皮,水肿型鼻息肉AQP-3阳性细胞率显著高于腺囊肿型和纤维型(P<0.01)。结论 AQP-3与鼻息肉的形成密切相关。更多还原

【Abstract】 Objective To investigate the expression of aquaporin-3(AQP-3) in nasal polyps. Methods With immunohistochemical technique,the expression of(AQP-3) was detected in the inferior turbinates of 50 cases and in the nasal polyps of 137 cases,of whom 78 cases were edematous type,32 cases glandular type and 27 cases cystic fibrous type.Results In both vessel endothelium and glandular epithelium,the positive rate of AQP-3 in nasal polyps of edematous type was higher than that in nasal polyps of glandular or cystic fibrous type(P<0.01).Conclusion There is a close relationship between AQP-3 and the formation of nasal polyps.更多还原