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2型糖尿病患者血浆糖化血红蛋白与高同型半胱氨酸水平相关性分析

The correlation between plasma GHbA1C and Hcy levels in patients with type 2 diabetes

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【作者】 王加平孟晓波秦文敬宋怀方梅燕

【Author】 WANG Jia-ping,MENG Xiao-bo,QIN Wen-jing,SONG Huai-fang,MEI Yan(Donghai People′s Hospital,Donghai,Jiangsu,222300)

【机构】 江苏省东海县人民医院检验科

【摘要】 目的分析了2型糖尿病(DM2)患者血浆GHbA1C水平与Hcy水平的相关性。方法应用直接酶法和两点速率法分别对61例2型糖尿病患者血浆GHbA1C水平与Hcy水平进行测定,并与35例正常健康者作比较。结果 2型糖尿病患者血浆GHbA1C水平与Hcy水平非常显著地高于正常对照组(P<0.01),血浆GHbA1C水平与Hcy水平呈显著正相关(P<0.01)。结论检测2型糖尿病患者血浆GHbA1C水平与Hcy水平的变化对疗效观察、预后判断均具有重要的临床价值。

【Abstract】 Objective To explore the correlation between plasma GHbA1C and Hcy levels in patients with type 2 diabetes.Methods Plasma GHbA1C(with enzymatic) Hcy(with Biochemistry)levels were measured in 61 patients with type 2 diabetes and 35 controls.Results Plasma GHbA1C and Hcy levels were significantly higher of the treatment group than those of the control(P<0.01).Plasma GHbA1C levels were significantly positively correlated with Hcy(P<0.01).Conclusion Detection of plasma GHbA1C and Hcy levels was useful for assessment of therapeutic efficacy and was of important clinical values in patients with type 2 diabetes.

  • 【文献出处】 实用临床医药杂志 ,Journal of Clinical Medicine in Practice , 编辑部邮箱 ,2011年23期
  • 【分类号】R587.1
  • 【被引频次】2
  • 【下载频次】55
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