【摘要】 目的探讨胸腺肽对恶性梗阻性黄疸病人术后感染并发症的防治作用。方法将2005年5月~2010年7月本院收治的132例恶性梗阻性黄疸的患者分为治疗组(63例)和对照组(69例),治疗组在手术治疗的基础上加用胸腺肽α1治疗,疗程为7 d,观察2组患者血液淋巴细胞变化以及术后感染的发生率。结果治疗组发生感染并发症13例,发生率20.6%(13/63),对照组发生感染并发症24例,发生率34.8%(24/69)。2组感染并发症发生率差异具有显著性差异(P<0.05)。术后第3、5、7、14天血淋巴细胞计数对照组明显低于治疗组(P<0.01)。结论 胸腺肽可有效降低恶性梗阻性黄疸术后感染并发症发生率及病死率。更多还原

【Abstract】 Objective To study the prevention and cure effect of thymosin on postoperative infectious complications of malignant obstructive jaundice.Methods One hundred and thirty-two cases with malignant obstructive jaundice from May 2005 to Jul.2010 were divided into the treatment group(n=43 cases) and control group(n=68 cases).Thymosin-α1 was used in the treatment group for 1 week on the basis of operation.The changes in lymphocyte count and the incidence of postoperative infection were observed.Results The incidence of postoperative infectious complications in treatment group,20.6%(13/63) was remarkably lower than that in control group(34.8%,24/69,P<0.05).The level of lymphocyte count in treatment group was remarkably lower than that in control group during the 3rd,5th,7th and 14th days(P<0.01).Conclusion Thymosin could effectively reduce the malignant obstructive jaundice complication rate of postoperative infection and mortality.更多还原