【摘要】 目的了解异甘草酸镁对慢性重症肝炎患者肝脏储备功能的影响。方法 120例慢性重症肝炎患者分为治疗组(n=60),静滴异甘草酸镁150 mg/d,连续30 d;对照组(n=60),静滴甘草酸二胺150 mg/d,连续30 d;30 d后检测两组肝功能指标及肝脏储备功能的变化。结果两组肝功能指标及肝脏储备功能较治疗前明显好转(P<0.05),治疗组与对照组比有统计学意义(P<0.05)。结论异甘草酸镁能显著减轻肝脏损伤程度,提高其储备功能,且耐受性良好,无明显不良反应。更多还原

【Abstract】 Objective To understand the effect of magnesium isoglycyrrhizinate on hepatic reserve function in patients with chronic severe hepatitis.Methods 120 patients with chronic acute hepatitis were divided into treatment group(n=60),which received the injection of magnesium isoglycyrrhizinate of 150 mg every day for 30 continuous days and control group(n=60) receiving the injection of diammonium glycyrrhizinate of 150 mg every day for 30 continuous days.The changes of the liver function indices and the hepatic reserve function were determinated 30 days after treatment.Results Thirty days after treatment,the liver function indices and the hepatic reserve function in both groups were improved(P<0.05).There was more statistically significance in the treatment group,compared with the control group(P<0.05).Conclusions The magnesium isoglycyrrhizinate can greatly reduce the damage of liver and raise the hepatic reserve function.There is a good toleration and no obvious side effects have been found.更多还原