【摘要】 目的:探讨急诊经桡动脉冠脉介入治疗(percutaneous coronary intervention,PCI)的安全性、有效性。方法:观察发病12 h内急性ST段抬高心肌梗死患者178例,其中121例经桡动脉(TRA)急诊PCI,57例经股动脉(TFA)急诊PCI。所有患者静脉应用替罗非班及其他正规治疗,观察手术及住院情况。结果:两组穿刺成功率、穿刺至首次球囊扩张时间、手术成功率、住院期间主要不良心脏事件比较均差异无统计学意义(P>0.05)。手术时间TRA组较短(33.2±14.7)分钟vs(40.5±15.7)分钟,P<0.01)。依从性TRA组达84.3%,明显高于TFA组26.3%(P<0.01)。血管并发症TRA组明显少于TFA组(4.1%vs 28.1%,P<0.01)。结论:在强化抗栓条件下,相对于股动脉途径,急诊经桡动脉PCI有相似的有效性及安全性,而且并发症较少。更多还原

【Abstract】 Objective:To observe the safety and efficacy of transradial approach primary percutaneous coronary intervention(PCI) for treating acute myocardial infarction(AMI).Methods:178 patients with AMI <12 h treated by PCI were included in the research.The radial arterial approach(TRA) was used in 121 cases,and the femoral arterial approach(TFA) in 57cases.All cases were used intravenous tirofiban and other standard therapy.The procedure and hospitalization were observed.Results:The successful rates of puncture and procedure,puncture to first balloon-inflation time and the major adverse cardiac event in duration of hospital stay were similar in both two groups.However,the procedure time was(33.2±14.7) min in TRA group vs.(40.5±15.7) min in TFA group(P=0.003).The compliance of puncture was significant higher in TRA group compared with TFA group(84.3% vs.28.1%,P<0.005).The vascular complication was significant decreased in TRA group compared with TFA group(4.1% vs.28.1%,P<0.005).Conclusion:Under condition of intensive antithrombotic treatment,transradial approach primary PCI for AMI is safe and effective,which is similar to TFA,moreover less vascular complications.更多还原