【摘要】 目的:观察放射治疗配合紫杉醇化疗对食管癌的临床疗效。方法:对173例食管癌病人根据不同的治疗方法分为两组:单纯放射治疗组(单放组)和放射治疗同步化疗组(放化疗组)。单放组80例,采用常规设野放疗,DT 65~70 Gy;放化疗组93例,放疗方法及剂量同单放组,化疗采用紫杉醇每周同步方案。两组均随访2年。结果:局部近期疗效放化疗组好于单放组,两组差异有显著性(P<0.05)。放化疗组与单放组1、2年生存率单放组为51.3%(41/80)、32.5%(26/80),同步放化组为87%(81/93)、68.8%(64/93)。两组差异有显著性(P<0.05)。结论:同步放化疗优于单纯放射治疗,可明显提高食管癌的疗效。更多还原

【Abstract】 Objective:To investigate the effect of radiotherapy combined with paclitaxel on esophageal cancer.Methods:173 cases of esophageal cancer were divided into two groups.The simple radiotherapy group(80 cases) received the conventional radiotherapy with a total of 65～70 Gy,and the concurrent radiochemotherapy group(93 cases) was treated by the radiotherapy with the same method and same dosage plus the chemotherapy with weekly paclitaxel.Both groups were followed up for 2 years.Results:The local and short term effect in the radiochemotherapy group was better than that in the simple radiotherapy group with the statistical difference(P<0.05).The 1-year and 2-year survival rates were 51.3%(421/80) and 32.5%(26/80) in the simple radiotherapy group and 76.3%(71/93) and 58.1%(54/93) in the radiochemotherapy group with statistical difference(P<0.05).Conclusion:Concurrent radiochemotherapy is superior to simple radiotherapy in treating esophageal cancer,which increases the curative effect.更多还原