节点文献

纳米Eu₂O₃/硫酸酯化壳聚糖杂化材料的制备及其抗凝血性能研究

Synthesis and Anticoagulant Action of Sulfated Chitosan/Eu₂O₃ Nano-Oxides Hybrid Materials

推荐 CAJ下载
PDF下载
不支持迅雷等下载工具，请取消加速工具后下载。

【Author】 Wang Kunjie1,2,Li Hongxia1,Ye Qingyuan1,Wang Yi1,Zhang Deyi1,Feng Huixia1,Song Yumin2(1.College of Petrochemical Technology,Lanzhou University of Technology,Lanzhou 730050,China;2.College of Chemistry and Chemical Engineering,Northwest Normal University,Lanzhou 730070,China)

【机构】兰州理工大学石油化工学院；西北师范大学化学化工学院；

【摘要】利用表面接枝的方法制备了纳米Eu2O3/硫酸酯化壳聚糖杂化材料,并用IR,TG和SEM等方法对产物进行了表征,结果表明硫酸酯化壳聚糖接枝在了经过活化后的纳米氧化物表面,细胞毒性实验证明材料具有较低的细胞毒性和较好的细胞相容性。抗凝血实验说明材料具有良好的抗凝血性能。表面接枝方法提高了壳聚糖类化合物的抗凝作用,弥补了此类化合物在抗凝方面的不足。更多还原

【Abstract】 The Eu2O3 nano-oxides surface was modified by 3-glycidoxypropyltrimethoxysilane.The hybrid materials of sulfated chitosan and Eu2O3 nano-oxides were prepared by the method of graft.And the materials were characterized by IR,TG and SEM.The results showed that the sulfated chitosan was grafted on the surface of Eu2O3 nano-oxides,which was modified by KH-560.The results of cell adhesion experiment showed that the material had lower cell toxicity and better cell adhesion.The experiment of anticoagulant showed that the material has better anticoagulant action.更多还原