【摘要】 目的了解急性白血病患者凝血酶激活的纤溶抑制物抗原(TAFI:Ag)水平的变化及其临床意义。方法应用ELISA法检测50例急性白血病病人及30例正常人的TAFI:Ag水平,并进行统计学比较。结果急性白血病病人治疗前TAFI:Ag水平为82.57±18.51μg/m l,较正常对照组的46.19±12.59μg/m l显著增高(P<0.01)。结论急性白血病病人TAFI:Ag水平异常增高,随病情好转逐渐改善。更多还原

【Abstract】 Objective To measure the levels of plasma thrombin-activatable fibrinolysis inhitor antigen(TAFI:Ag) in patients with acute leukemia,and clinical significance.Methods 50 cases acute leukemia patients were selected into the study were measured before and after therapy.The levels of TAFI:Ag were measured by ELISA,control group 30 cases.Results Compared with control group,plasma levels of TAFI:Ag were elevated before treatment in acute leukemia patients(P<0.01).After complete remission,TAFI:Ag decreased into normal levels(P>0.05).Compared with normal group,plasma levels of thrombin-activated fibrinolysis inhitor:C were reduced before treatment in acute leukemia patients(P<0.01).After complete remission,TAFI:Ag increased into normal levels(P>0.05).Conclusion Fibrinolysis existed in acute leukemia patients and the decrease of anti-fibrinolysis maybe the main reason of hemorrhage,so improving the levels of TAFI C can reduce the chances of hemorrhage in acute leukemia.更多还原