【摘要】 [目的]探讨乌司他汀联合生长抑素治疗重症急性胰腺炎的疗效。[方法]选择62例确诊为重症急性胰腺炎患者,随机分为对照组30例和治疗组32例,两组患者均采用常规治疗,包括禁食、胃肠减压、抗炎、抑制胰酶分泌等对症支持治疗。治疗组在上述基础上给予乌司他汀、生长抑素,对照组仅单用生长抑素,14d为1个疗程,比较两组的疗效以及临床症状缓解情况。[结果]治疗组腹痛消失时间、血尿淀粉酶恢复正常时间、平均住院时间方面均明显短于对照组(P﹤0.01)。两组总有效率比较差异有统计学意义(χ2=8.375,P﹤0.01)。[结论]乌司他汀联合生长抑素治疗重症急性胰腺炎临床效果显著,可以明显改善患者的临床症状及体征,值得广泛推广和应用。更多还原

【Abstract】 [Objective]To discuss the ulinastatin combined with somatostatin in treatment of severe acute pancreatitis.[Methods]62 patients diagnosed with severe acute pancreatitis were randomly divided into control group and treatment group,two groups were treated with conventional therapy,including fasting,gastrointestinal decompression,anti-inflammatory,inhibit pancreatic secretion symptomatic and supportive treatment.Treatment group based on the above was given ulinastatin,somatostatin,while somatostatin was used alone in the control group.14d was a course of treatment.Then compared the efficacy and clinical remission in the two groups.[Results]The extinction time of abdominal pain,the recovery time of urine amylase,the average hospitalization time in the treatment group were significantly shorter than in the control group(P﹤0.01).The total effective rate was statistically different(χ2 = 8.375,P﹤0.01).[Conclusion]Ulinastatin combined with somatostatin in treatment of severe acute pancreatitis has significant clinical effect,which can improve clinical symptoms and signs,it should be popularized and applied in clinic.更多还原