【摘要】 [目的]观察早期应用倍他乐克对于急性心肌梗死(AMI)患者的临床效果及对左心室收缩功能的影响。[方法]2007年6月～2010年6月,122例AMI患者随机分为两组,对照组61例仅采用常规治疗,观察组61例在常规治疗基础上早期应用倍他乐克治疗,比较观察两组的临床效果和左心室收缩功能指标的变化。[结果]观察组的心衰加重率、心源性猝死率和住院总死亡率均明显低于对照组,两组比较差异有统计学意义(P﹤0.05)。观察组治疗后LVEDd水平明显下降,LVFS和LVEF水平明显升高,与治疗前差异有统计学意义(P﹤0.05);而对照组治疗前后比较,差异无统计学意义(P﹥0.05)。观察组治疗后LVEDd、LVFS和LVEF水平与同期对照差异有统计学意义(P﹤0.05)。[结论]早期应用倍他乐克对于AMI患者能够明显降低心衰加重率、心源性猝死率和住院总死亡率,并且能明显改善左心室收缩功能,值得临床推广应用。更多还原

【Abstract】 [Objective]To observe the clinical observation of early used betaloc in treatment with acute myocardial infarction(AMI)and its affection with left ventricular systolic function.[Methods]From June 2007 to June 2010,122 cases of AMI patients were randomly classified into two groups,which control group with 61 cases was treated with normal therapy and observation group with 61 cases was treated with betaloc at the basis of normal therapy.The clinical effect and left ventricular systolic function were observed and compared.[Results]The heart failure worsen rate,sudden cardiac death rate of total hospitalization mortality rate in observation group were significantly lower than those in control group(P﹤0.05).Compared with pre-treatment,the LVEDd was significantly decreased(P﹤0.05),LVFS and LVEF were significantly decreased(P﹤0.05)after treatment in observation group while no significant difference was found in control group(P﹥0.05).Moreover,the level of LVEDd,LVFS and LVEF in observation group after treatment were significantly different from those in control group(P﹤0.05).[Conclusion]Early used betaloc in treatment with AMI can decrease the heart failure worsen rate,sudden cardiac death rate of total hospitalization mortality rate,and improve the left ventricular systolic function,which can be applied in clinic.更多还原