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生长抑素联合丹参治疗乙型肝炎肝硬化合并急性胰腺炎的临床研究
CLINICAL STUDY OF COMBINATION OF SANDOSTATIN WITH SALVIAE MILTIORRHIZAE(SM)IN TREATMENT OF HEPATITIS B CIRRHOSIS ASSOCIATED SEVERE ACUTE PANCREATITIS
【摘要】 [目的]探讨生长抑素联合丹参对乙型肝炎肝硬化合并急性胰腺炎(AP)的治疗作用。[方法]乙型肝炎肝硬化合并急性胰腺炎患者105例,随机分为4组:对照组、生长抑素组、丹参组、联合组(生长抑素+丹参),分别从临床表现、实验室检查及预后等方面进行总结分析。[结果]与对照组比较,生长抑素组、丹参组及联合组,血淀粉酶、尿淀粉酶、ALT、AST、TBIL均明显下降(P﹤0.05);与对照组比较,生长抑素组、丹参组及联合组,乙型肝炎病毒标志物及HBV-DNA定量比较差异不具有统计学意义(P﹥0.05)。[结论]联合应用生长抑素和丹参治疗乙型肝炎肝硬化合并急性胰腺炎(AP)有协同作用,疗效优于单纯的西药治疗。
【Abstract】 [Objective]To investigate the therapeutic effects of combining somatostatin(SS)with salviae miltiorrhizae(SM)in curing Hepatitis B cirrhosis associated severe acute pancreatitis.[Methods]105 patients were randomly divided into four groups:control group,SS group,SM group and combination group. Changes of clinical symptoms,laboratory results and prognosis were observed.[Results]Compared with control group,hemodiastase,urinary amylase,ALT,AST and TBIL in SS,SM and combination group were significantly lower(P﹤0.05);Compared with control group:virus markers of hepatitis and the content of HBV-DNA were not significant in other groups(P﹥0.05).[Conclusion]The therapeutic effect of combining somatostatin with salviae miltiorrhizae in the treatment of Hepatitis B cirrhosis associated severe acute pancreatitis is superior to using western medicine alone.
【Key words】 Cirrhosis; Pancreatitis; Acute; Somatostatin; Salviae miltiorrhizae; Integrated;
- 【文献出处】 现代预防医学 ,Modern Preventive Medicine , 编辑部邮箱 ,2011年15期
- 【分类号】R576;R575.2
- 【被引频次】3
- 【下载频次】111