【摘要】 [目的]分析河北省2005～2009年流行性脑脊髓膜炎(流脑)死亡病例,为预防控制流脑及临床诊断提供依据。[方法]对2005～2009年河北省流脑死亡病例开展流行病学、临床和实验室相关特征分析,并对不同年份流脑病例的临床诊断环节进行比较。[结果]河北省流脑死亡病例多发生于12月和1～5月占死亡病例总数的89.47%,且5岁以下儿童占76.30%,尤其是散居儿童,但无男女性别差异;地区差异较强;临床特征比较明显;实验室检测以A群较多,但C群有增加趋势;仅发生一起暴发疫情。[结论]河北省流脑报告病例发病率呈下降趋势,但病死率增加,死亡病例的平均诊断时间较长,未接种疫苗者多发,地域差异明显。上述特征可能与临床诊断不及时、疫苗接种率低和地域卫生习惯等有关。更多还原

【Abstract】 [Objective]The study was conducted to make a preliminary analysis of deaths of epidemic cerebrospinal meningitis for the prevention and control of ECM and to provide bases for clinical diagnosis in Hebei Province during 2005-2009.[Methods]Analysed the epidemiological,clinical and laboratory-related features of meningitis deaths,analyzed the time of diagnosis on epidemic cerebrospinal meningitis and the time from the onset to the death in Hebei Province from 2005 to 2009.[Results]In Hebei,the death time of meningitis occurred in December and from January to May,and the percent in all death cases was 89.47%.ECM mainly occurred in children under 5 years,especially in children with scattered living,and the percent was 76.30% in all death cases,there was no gender differences between males and females;ECM with strong regional differences and obvious clinical features;A group was found more in laboratory tests,but the C group with an upward trend;only one meningitis outbreak occurred in the province.[Conclusion]In Hebei Province,the incidence of meningitis is with a downward trend,but the fatality rate increases.Death cases have long average diagnosis time,un-vaccinated children and the difference region are found more in death cases.The above characteristics are related with delayed clinical diagnosis,low vaccination rate and differences of regional living and health habits,etc.更多还原