【摘要】 [目的]研究牛磺酸防治酒精性脂肪肝的作用机制。[方法]将小鼠随机分为5组,包括正常对照组、酒精性脂肪肝模型组、牛磺酸高中低3个剂量组。30d后分别检测肝脏中脂褐质LF、血清MDA、SOD以及GSH-Px等指标。[结果]牛磺酸能显著降低小鼠血清MDA和肝脏中脂褐质LF的含量,并增强血清中SOD以及GSH-PX的活性。[结论]牛磺酸可能通过抗氧化的途径来减轻酒精性脂肪对小鼠的损伤。更多还原

【Abstract】 [Objective]To study the therapeutic effect of taurine on the alcoholic fatty liver.[Methods]Mice were randomized into 5 groups,including normal control group,model group of alcoholic fatty liver and 3 interventional taurine groups.30 days later,the contents of LF in the liver,MDA,SOD and GSH-PX activities were measured.[Results]Taurine reduced the levels of MDA and LF significantly and also increased the activities of SOD and GSH-PX.[Conclusion]Taurine may improve the alcoholic fatty liver by its anti-oxidative action.更多还原