【摘要】 背景:研究认为肌酸补剂能够安全有效的消除增龄性骨骼肌质量降低。目的:综述关于肌酸补剂对老年人骨骼肌能量代谢,骨骼肌运动能力及生命质量影响的文献,探讨肌酸为什么对延迟肌肉衰减症的发生是有效的。方法:以"肌酸;老年人;骨骼肌;磷酸肌酸;力量"为中文检索词,以"creatine;oldadults;skeletal muscle;phosphocreatine;strength"为英文检索词。应用计算机检索PubMed数据库和中国知网中文期刊全文数据库2011-03前发表的相关文章。纳入肌酸补剂对老年人骨骼肌能量代谢和运动能力的影响研究相关的文献,排除重复性研究。结果与结论:共检测到72篇文献,排除无关重复的文献,保留38篇文献进行综述。研究了近年有关肌酸对骨骼肌细胞内能量代谢,骨骼肌形态,肌酸对老年人生活质量影响的研究文献。结果表明肌酸能够增强老年人的肌肉力量,使肌肉肥大,运动能力提高。肌酸是一种安全,价格便宜和有效的营养补剂,尤其结合抗阻力训练时服用对减缓由于增龄引起的肌肉失用效果很好。更多还原

【Abstract】 BACKGROUND:Research shows that creatine supplementation is a safe and effective method to diminish age-related declines in muscle mass and strength.OBJECTIVE:To summarize studies about the effects of creatine supplementation on skeletal muscle energy metabolism,exercise capacity and life quality in old adults.METHODS:An online search of PubMed database and CNKI was performed using key words of "creatine;old adults;skeletal muscle;phosphocreatine;strength" for articles published before March 2011,both in English and Chinese.Papers about effects of creatine supplementation on skeletal muscle energy metabolism and exercise capacity in old adults were included,and repetitive researches were excluded.RESULTS AND CONCLUSION:A total of 72 documents were retrieved,and 38 articles were retained after depleting unrelated and repetitive ones.The recent researches concerning the effects of creatine supplementation on intramuscular energy metabolism,skeletal muscle morphology and life quality in old adults were summarized.Creatine can increase muscle strength,induce muscle hypertrophy and improve the exercise capacity of old adults.Creatine supplementation is a safe,inexpensive and effective nutritional intervention.It can slow the muscle wasting rate associated with aging,especially when consumed in conjunction with resistance training.更多还原