【摘要】 目的探讨Apollo支架治疗症状性颅内动脉狭窄的安全性及临床疗效。方法采用Apollo支架植入治疗22例(24支)症状性颅内动脉狭窄患者,随访3～28个月,平均14个月,分别观察技术成功率和围手术期并发症、手术前后神经功能缺损程度、随访期间支架内再狭窄发生情况,以及脑卒中复发率和病死率。结果 Apollo支架植入治疗症状性颅内动脉狭窄的技术成功率为91.67%(22/24),平均狭窄率由手术前(73.23±9.59)%降至手术后(4.12±9.17)%(t=3.325,P=0.005)。围手术期未发生手术相关并发症,手术后神经功能缺损程度显著改善[美国国立卫生研究院卒中量表(NIHSS)评分:(0.59±1.35)比(0.59±1.74);t=2.718,P=0.015]。临床随访无脑卒中复发或死亡病例,CTA随访无支架内再狭窄。结论 Apollo支架植入治疗症状性颅内动脉狭窄可行且安全有效。更多还原

【Abstract】 Objective To explore the safety and effect of angioplasty with Apollo stent for symptomatic intracranial arterial stenosis.Methods Twenty-two symptomatic intracranial arterial stenosis patients(24 arteries) underwent Apollo stent placement.The follow-up period was 3-28 months(average 14 months).Successful rate,perioperative complications,pre- and post - operative National Institute of Health Stroke Scale(NIHSS),in-sent restenosis(ISR),stroke recurrence and case-fatality rate were asessed. Results Procedural and clinical success was achieved in 22(91.67%) target vessels.The degree of stenosis was reduced from the baseline of(73.23±9.59)%to(4.12±9.17)%after stenting(t = 3.325,P= 0.005).No perioperative complications occurred.Neural function was improved(NIHSS score: postoperation,0.59±1.35 vs.preoperation,0.59+ 1.74;t=2.718,P=0.015).No in-stent restenosis was seen by CT angiography(CTA).No patients had stroke recurrence or died.Conclusion Angioplasty and stenting with Apollo stent for treating symptomatic intracranial arterial stenosis is safe and effective.更多还原