【摘要】 目的:调查河南、新疆、广东、云南四地人类免疫缺陷病毒(human i mmunodeficiency virus,HIV)感染者和艾滋病患者的证素特点,分析艾滋病中医病因病机中病性证素的分布特点。方法:采用流行病学现况调查的方法。通过文献研究和专家论证,制定临床调查表,制定实施方案,培训调查员,进行现况调查。采用《WF-Ⅲ中医(辅助)诊疗系统》进行证素分析,比较河南、新疆、广东、云南四地艾滋病病性证素分布差异,分析艾滋病病因病机中的病性证素特点。结果:2008年10月至2010年8月调查河南、广东、新疆、云南四地HIV感染者和艾滋病患者分别为276、126、120、86例,合计608例。四地HIV感染和艾滋病的主要病性证素均以气虚、血虚、阳虚、阴虚、湿、痰等积分较高,但又有地域特点,如河南的各证素积分均较高,各地的证素积分中广东病性证素湿积分较高,新疆病性证素阴虚积分较高,无症状HIV感染者的积分低于艾滋病患者。结论:尽管地域不同,四省区艾滋病在病性证素上基本相似,并且各个证素随病情进展而积分增加,"艾毒伤元"假说可以概括艾滋病的中医病因病机特点。更多还原

【Abstract】 Objective: To study the characteristics of traditional Chinese medicine (TCM) syndrome factors of patients from different areas of China with human immunodeficiency virus (HIV) infection or acquired immunodeficiency syndrome (AIDS).Methods: A cross-sectional investigation study was conducted in Henan, Guangdong and Yunnan Provinces and Xinjiang Uygur Autonomous Region of China from October 2008 to August 2010. Based on literature review and expert opinion, a clinical questionnaire of TCM syndromes was drawn up. This survey was carried out after the investigators were professionally trained. Wenfeng Ⅲ Auxiliary Diagnosis and Treat System of TCM was used to analyze the frequencies of AIDS patients’ signs and symptoms with scores above 70 of syndrome factors respectively. Based on this work, syndrome factors of AIDS were analyzed in different areas. Results: There were 608 HIV/AIDS cases investigated from October 2008 to August 2010 in total; among them, 276 cases were from Henan, 126 cases from Guangdong, 120 cases from Xinjiang and 86 cases from Yunnan. The results of syndrome factor analysis indicated that the syndromes of four provinces were similar. HIV/AIDS patients in the four areas exhibited qi deficiency, blood deficiency, yin deficiency, yang deficiency, dampness, phlegm, qi stagnation and essence deficiency syndromes. Patients in each area also had their own characteristics, such as that the scores of dampness of Guangdong and yin deficiency of Xinjiang were higher than the other syndromes, whereas the scores of Henan Province were higher than the other areas. AIDS patients had higher scores of syndromes than HIV-infected patients.Conclusion: HIV/AIDS patients from different areas had similar syndrome elements. The theory of "AIDS toxin injurying primordial qi" can sum up the TCM etiology and pathogenesis of HIV/AIDS.更多还原