【摘要】 目的:探讨子宫平滑肌肿瘤临床病理特征。方法:对246例子宫平滑肌肿瘤的临床病理资料进行回顾性分析。结果:子宫平滑肌肿瘤发病高峰年龄为40～50岁,可伴内膜增生或腺肌病,同时与卵巢、宫颈多种良恶性病变并存。246例子宫平滑肌肿瘤中,91.4%为普通型良性平滑肌瘤;6.9%为平滑肌瘤特殊组织学类型;0.8%为平滑肌肉瘤;0.8%为恶性潜能未定的平滑肌肿瘤。结论:子宫平滑肌肿瘤是妇科常见肿瘤。在子宫平滑肌肿瘤良恶性的鉴别诊断中,凝固性肿瘤细胞坏死、弥漫性中到重度核的非典型性、核分裂象增多(≥10/10HPF)是诊断的重要标准。但预期肿瘤的生物学行为还要综合各种临床病理参数。更多还原

【Abstract】 Objective To investigate the clinicopathological features of uterine smooth muscle tumors.Methods Clinical and pathological data from 246 cases of uterine smooth muscle tumors were analyzed retrospectively.Results The peak time for incidence of uterine smooth muscle tumors is in patients with 40 ～ 50 years old.Uterine smooth muscle tumors could co-exist with other diseases such as endometrial hyperplasia,adenomyosis,all kinds of benign or malignant pathological change of cervix and ovary.Among 246 cases,the percentage for usual leiomyoma,special leiomyoma,leiomyosarcoma,and smooth muscle tumor with uncertain malignant potential is 91.4%,6.9%,0.8%,and 0.8%,respectively.Conclusion Uterine smooth muscle tumors is gynecological common tumors.Coagulative(tumor) necrosis,severe nuclear atypia,and high mitotic rate are major criterion for diagnosis of benign and malignant tumors.Multiple clinicopathologic factors should be analyzed to predict biological behavior of uterine smooth muscle tumors.更多还原