【摘要】 Peptaibols是一类由非核糖体肽合成酶(NRPSs)合成的富含α-氨基异丁酸(Aib)的特殊抗菌肽。目前发现的317种peptaibols大多由木霉属真菌产生。本文对木霉产生的这类特殊抗菌肽-peptaibols的多样性、发酵、分离纯化、鉴定及其生物合成进行了综述。更多还原

【Abstract】 Peptaibols are a family of antimicrobial peptides,which are synthesized by non-ribosomal peptide synthetases(NRPS) and contain high proportions of α-aminoisobytyric acid(Aib).Up to now,317 peptaibols have been identified,and the majority of them are produced by Trichoderma strains.In this review,we described the diversity,fermation,purification,identification and biosynthesis of peptaibols from Trichoderma.更多还原