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Preparation of Filling Porous Osteoconduction Materials and Its Animal Experiment Study

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【作者】 陈晓明

【Author】 CHEN Xiaoming1,WANG Jing1,CHEN Weimin2,LI Dezhong3 (1.Biomedical Materials and Engineering Research Center,Wuhan University of Technology,Wuhan 430070,China;2.Animal Experiment Center,Zhongnan Hospital of Wuhan University,Wuhan 430077,China;3.Devision of Electron Microscope,Guangzhou Military Area Wuhan General Hospital,Wuhan 430070,China)

【机构】 Biomedical Materials and Engineering Research Center,Wuhan University of Technology

【摘要】 Titanium rods were processed into implant samples with cavity and groove in which was filled with HAP/β-TCP porous osteoconduction composite materials in order to increase the mechanical stability of the implant in vivo.The phase compositions of the composite was characterized by X-ray diffraction (XRD) and scanning electron microscopy(SEM).Histological evaluation showed that the biogradable composite could enhanced the ability of new bone formation.The composite can conduct new bone tissue growing into the cavities gradually after implanted into animal,and then achieve mechanical fixation.The filling biogradable compound exhibited excellent biocompatibility,which combined with the new bone tissues tightly without inflammation and loosing.

【Abstract】 Titanium rods were processed into implant samples with cavity and groove in which was filled with HAP/β-TCP porous osteoconduction composite materials in order to increase the mechanical stability of the implant in vivo.The phase compositions of the composite was characterized by X-ray diffraction (XRD) and scanning electron microscopy(SEM).Histological evaluation showed that the biogradable composite could enhanced the ability of new bone formation.The composite can conduct new bone tissue growing into the cavities gradually after implanted into animal,and then achieve mechanical fixation.The filling biogradable compound exhibited excellent biocompatibility,which combined with the new bone tissues tightly without inflammation and loosing.

【基金】 Funded by the National Natural Science Foundation of China (No.50872099)
  • 【文献出处】 Journal of Wuhan University of Technology(Materials Science Edition) ,武汉理工大学学报(材料科学版)(英文版) , 编辑部邮箱 ,2011年02期
  • 【分类号】TB33
  • 【下载频次】32
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