【摘要】 目的探讨Ⅲ型前列腺炎(CCPS)治疗前后血清前列腺特异性抗原(PSA)变化的临床意义。方法对经过筛查出的260例PSA≥4 ng/mL的Ⅲ型前列腺炎患者,在治疗前后行PSA检测并根据治疗前、后PSA水平及前列腺穿刺活检的结果分A、B、C三组进行对比分析,了解各组治疗前后PSA水平及前列腺癌诊断阳性率。结果 A组PSA平均值由治疗前的(6.54±1.86)ng/mL降至治疗后的(3.28±1.86)ng/mL,差异均有显著性统计学意义(P<0.01);B、C组治疗前后PSA值比较差异均无统计学意义;治疗后前列腺癌诊断阳性率明显高于治疗前,差异均有显著性统计学意义(P<0.01)。结论 PSA可用于监测前列腺炎预后情况,对于治疗后其PSA≥4 ng/mL的患者,活检可提高诊断阳性率,对早期筛查前列腺癌有重要的临床意义。更多还原

【Abstract】 Objective To study the clinical significance of the changes in serum PSA before and after the treatment of Type Ⅲ prostatitis.Methods 260 patients with Type Ⅲ prostatitis with PSA≥4 ng/ml were screened out and divided into three groups of A,B and C according to PSA levels and prostate biopsy before and after treatment.PSA levels and positive rate of diagnosis of prostate cancer PSA were studied.Results Average value of PSA was reduced from(6.54±1.86)ng/ml of pre-treatment to(3.28±1.86)ng/ml of post-treatment in group A,and with statistical significance(P<0.05),but there was no statistical difference in PSA levels in group B or group C.Positive diagnosis rate of prostate cancer after treatment was significantly higher than before treatment(P<0.05).Conclusion PSA can be used to monitor the prognosis of prostatitis.For patients with PSA≥4 ng/ml after the treatment,biopsy can increase positive diagnostic rate,indicating its clinical significance in screening for prostate cancer.更多还原