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玻璃化冻融胚胎保存时间对胚胎复苏结局的影响

Effect of cryopreservation duration on the outcomes of vitrified-thawed embryo transfer

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【作者】 赵庆红杨菁尹太郎龙文李凤和

【Author】 ZHAO Qing-hong,YANG Jing~*,YIN Tai-lang,LONG Wen,LI Feng-he Reproductive Medicine Center,Renmin Hospital of Wuhan University,Wuhan 430060

【机构】 武汉大学人民医院生殖医学中心

【摘要】 目的探讨辅助生殖技术中影响玻璃化冻融胚胎保存时间对胚胎复苏结局的影响。方法将复苏后全部卵裂球存活的胚胎定义完全存活胚胎。对367个冻融胚胎移植(FET)周期的相关资料进行回顾性统计学分析,根据冻融胚胎保存时间进行分组,分为<6、≥6~<12及≥12~1 9个月A、B、C 3组,比较各组的胚胎复苏率、完全存活胚胎率、胚胎种植率和临床妊娠率。结果三组患者的胚胎复苏率、完全胚胎存活率、胚胎种植率及临床妊娠率,组问比较均无显著性差异(P>0.05)。结论在玻璃化FET周期,胚胎冷冻保存时间对解冻后胚胎质量及FET结局没有影响,因此可以灵活掌握FET时间。

【Abstract】 Objective:To compare the outcome of vitrified embryos with different cryopreservation duration in assisted reproductive technology. Methods:A retrospective statistical analysis was performed on 367 cycles of frozen-thawed embryo transfer.The cycles were divided into 3 groups according to the cryopreservaton durations of vitrified embryos(<6,6-12,12-19 months).The rates of embryo survival and intact embryo survival after thawing,embryo implantation and clinical pregnancy were compared among the three groups. Results:There was no significant difference in observed parameters among the three groups (P>0.05). Conclusion:The cryopreservation duration of vitrified embryo did not affect the outcome of frozenthawed embryo transfer.

【关键词】 冻融胚胎玻璃化妊娠率
【Key words】 Frozen-thawed embryoVitrificationPregnancy rate
  • 【文献出处】 生殖医学杂志 ,Journal of Reproductive Medicine , 编辑部邮箱 ,2011年04期
  • 【分类号】R714.8
  • 【被引频次】5
  • 【下载频次】72
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