【摘要】 目的观察强肌健力方对脾虚证大鼠的脾脏、胸腺、肾上腺超微结构的影响。进一步了解该方药对改善脾虚证的意义。方法将SD大鼠40只随机分为正常对照组、脾虚模型组、强肌健力组、右归丸组。采用大黄复制脾虚模型,分别给予蒸馏水、强肌健力方、右归丸灌胃。比较各组动物脾脏、胸腺、肾上腺超微结构的改变。结果正常对照组脾小体中淋巴细胞、胸腺皮质淋巴细胞、肾上腺皮质细胞的超微结构均正常,而脾虚模型组大鼠的脾脏、胸腺、肾上腺超微结构均有明显的损伤现象,强肌健力方对已受损伤的各脏器的超微结构得以修复,恢复到接近正常水平。结论强肌健力方对脾虚证大鼠受损的脾脏、胸腺、肾上腺组织具有一定的保护作用。更多还原

【Abstract】 Objective To observe the effects of Qiangji Jianli Fang on the ultrastructural changes of spleen thymus and adrenal gland in rats with spleen deficiency syndrome.Methods Forty healthy male SD rats were randomly divided into 4 groups: normal group,model group,QJJL preparation group and Yougui Wan-treated group.Rat model of spleen deficiency syndrome was established by gavage with rhubarb,and spleen,thymus and adrenal gland ultrastmctural changes were observed.Results Ultrastructure of splenic corpuscle lymphocytes,thymic cortex lymphocytes and adrenocortical cells in normal group was normal,but the ultrastructure of spleen,thymus and adrenal in deficiency model group had obvious damage phenomenon.Qiangji Jianli Fang,could repair the damaged ultrastructure of various organs returning to near normal levels.Conclusion Qiangji Jianli Fang has a protective effect against the damaged spleen,thymus,adrenal gland in spleen deficiency rats.更多还原