【摘要】 目的探讨中医体质类型与原发性肝癌TNM分期及Okuda分期的相关性。方法采用标准化的9种中医体质分类量表对151例原发性肝癌患者进行中医体质辨识,并就体质类型与肝癌TNM分期及Okuda分期进行Crosstabs相关性分析。结果Ⅰ期(T1N0M0)患者的偏颇体质主要以气虚质、淤血质、湿热质和阳虚质为主;Ⅱ期(T2N0M0)以平和质为主,偏颇体质阳虚质最多,其次是气虚质和阴虚质;ⅢA期(T3N0M0)以气虚质和湿热质为主,余偏颇体质分别是阳虚质、气郁质和淤血质;ⅢB期(T4N0M0)亦以平和质为主,偏颇体质主要是气虚质和阳虚质,其次是淤血质;ⅢC期(TXN1M0)偏颇体质以气虚质居多,其次是阳虚质、气郁质,痰湿质、湿热质和特禀质;Ⅳ期(TXNXM1)以阳虚质为主,余偏颇体质按由多至少的顺序依次是气虚质、气郁质、特禀质和痰湿质。Okuda分期Ⅰ期患者偏颇体质以湿热质、气郁质、气虚质和阳虚质为主,其次是淤血质和阴虚质;Ⅱ期以气虚、阳虚和湿热质为主,淤血质和气郁质次之;Ⅲ期以气虚质和阳虚质为主,其次是痰湿质和湿热质。结论体质类型与西医TNM分期及Okuda分期有一定的相关性,TNMⅠ、Ⅱ期患者以气虚质和阳虚质居多,ⅢA期以气虚质和湿热质为主,ⅢB期以上患者以阳虚质、气虚质为主。Okuda分期Ⅰ期、Ⅱ期以气虚、阳虚和湿热质为主;Ⅲ期以气虚质和阳虚质为主。更多还原

【Abstract】 Objective To explore the correlation ship between Chinese medicine constitution patterns and TNM staging,Okuda staging of primary liver cancer. Methods Standardized classification measurement questionnaire of nine constitutions in Chinese medicine were used to investigate the Chinese medicine constitution of 151 primary liver cancer patients.The correlation ship between Chinese medicine constitution and TNM staging,Okuda staging of primary liver cancer was analyzed with crosstabs test. Results The biased constitutions of the patients at TNM stage Ⅰwere mostly "Qi"-deficiency type,blood-stasis type,wet-heat type and "Yang"-deficiency type.The constitution of the patients at TNM stage Ⅱ was mostly gentleness type,the biased constitution was mostly "Yang"-deficiency type,followed by "Qi"-deficiency type and "Yin"-deficiency type.The biased constitutions of those who at TNM stage ⅢA were mostly "Qi-"deficiency type and wet-heat type,followed by "Yang"-deficiency type,"Qi"-depression type and blood-stasis type.The constitution of the patients at TNM stage ⅢB was mostly gentleness type,too,the biased constitution was mostly "Qi-"deficiency type and "Yang-"deficiency type,then were blood-stasis type.The biased constitution of those who were at TNM stage ⅢC was mostly "Qi-"deficiency type,followed by "Yang-"deficiency type,"Qi"-depression type,phlegm-wetness type,Wet-heat type and special diathesis type.The biased constitution of those who at TNM stage Ⅳ were mostly "Yang-"deficiency type,followed by "Qi"-deficiency type,"Qi-"depression type,special diathesis type and phlegm-wetness type.The biased constitutions of the patients with Okuda stage Ⅰ were mostly wet-heat type,"Qi-"depression type,"Qi"-deficiency type and "Yang-"deficiency type,followed by blood-stasis type and Yin-deficiency type.While the patients at Okuda stage Ⅱ were mostly "Qi-"deficiency type,"Yang-"deficiency type and wet-heat type,followed by blood-stasis type and "Qi"-depression type.The patients at Okuda stage Ⅲ were mostly "Qi"-deficiency type and "Yang-"deficiency type,followed by phlegm-wetness type and wet-heat type. Conclusion There has certain correlation ship between the constitution in Chinese medicine and TNM staging,Okuda staging.The biased constitutions of the patients at TNM stage Ⅰand stage Ⅱ are mostly "Qi-"deficiency type and "Yang-"deficiency type,those who with stage ⅢA was mostly "Qi-"deficiency type and wet-heat type,and the patients with advanced PLC(stage ⅢB,ⅢC or Ⅳ) was mostly "Yang"-deficiency type and "Qi-"deficiency type.The biased constitutions of the patients at Okuda stage Ⅰand stage Ⅱ are mostly "Qi"-deficiency type,"Yang-"deficiency type and wet-heat type,while those who are at stage Ⅲ are mostly "Qi-"deficiency type and "Yang"-deficiency type.更多还原